| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-galactosidase |
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| Ligand | BDBM50204208 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1626901 (CHEMBL3869422) |
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| IC50 | 719000±n/a nM |
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| Citation |  Miyawaki, S; Hirokami, Y; Kinami, K; Hoshino, M; Minehira, D; Miyamoto, D; Nash, RJ; Fleet, GW; Adachi, I; Toyooka, N; Kato, A Strategy for designing selectivea-l-rhamnosidase inhibitors: Synthesis and biological evaluation of l-DMDP cyclic isothioureas. Bioorg Med Chem25:107-115 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-galactosidase |
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| Name: | Beta-galactosidase |
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| Synonyms: | β-galactosidase | BGAL_BOVIN | Beta-galactosidase/Glucosylceramidase | GLB1 |
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| Type: | Protein |
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| Mol. Mass.: | 73420.88 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | n/a |
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| Residue: | 653 |
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| Sequence: | MPGVVRLLALLLVPLLLGSARGLHNATQRTFQIDYRRNRFLKDGQPFRYISGSIHYFRVP
RFYWKDRLLKMKMAGLNAIQTYVAWNFHELQPGRYNFSGDHDVEHFIQLAHELGLLVILR
PGPYICAEWDMGGLPAWLLEKKSIVLRSSDPDYLAAVDKWLGVLLPKMRPLLYKNGGPII
TVQVENEYGSYLSCDYDYLRFLQKRFHDHLGEDVLLFTTDGVNERLLQCGALQGLYATVD
FSPGTNLTAAFMLQRKFEPTGPLVNSEFYTGWLDHWGQRHSTVSSKAVAFTLHDMLALGA
NVNMYMFIGGTNFAYWNGANIPYQPQPTSYDYDAPLSEAGDLTEKYFALRDIIQKFAKVP
EGPIPPSTPKFAYGKVALNKLKTVEDALNILCPSGPIKSVYPLTFIDVKQYFGFVLYRTM
LPEDCSDPTPLSSPLSGVHDRAYVSVNGVAQGILERESVITLNITGKAGATLDLLVENMG
RVNYGSSINDFKGLVSNLTLGSKILTNWEIFPLDMEDAVRSHLGTWGGRDRGYHNKARAH
SPPTYALPTFYVGNFTIPSGIADLPQDTFIQFPGWTKGQVWINGFNLGRYWPVRGPQMTL
FVPQHILVTSTPNTIVVLELEHAPCQDGGPELCTVEFVDKPVFRTVQTHRHAN
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| BDBM50204208 |
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| n/a |
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| Name | BDBM50204208 |
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| Synonyms: | CHEMBL3910143 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H20N2O3S |
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| Mol. Mass. | 260.353 |
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| SMILES | [H][C@@]12CS\C(=N\CCCC)N1[C@@H](CO)[C@H](O)[C@H]2O |r| |
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| Structure | 
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