| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1D adrenergic receptor |
|---|
| Ligand | BDBM50204306 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1627293 (CHEMBL3869814) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  McLeod, MC; Aubé, J; Frankowski, KJ Decahydrobenzoquinolin-5-one sigma receptor ligands: Divergent development of both sigma 1 and sigma 2 receptor selective examples. Bioorg Med Chem Lett26:5689-5694 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1D adrenergic receptor |
|---|
| Name: | Alpha-1D adrenergic receptor |
|---|
| Synonyms: | ADA1D_HUMAN | ADRA1A | ADRA1D | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1D-adrenoceptor | Alpha 1D-adrenoreceptor | Alpha adrenergic receptor (1a and 1d) | Alpha-1D adrenoceptor | Alpha-adrenergic receptor 1a | adrenergic Alpha1D |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 60485.82 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | adrenergic Alpha1D ADRA1D HUMAN::P25100 |
|---|
| Residue: | 572 |
|---|
| Sequence: | MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAG
SGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILS
VACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCC
TASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVP
PDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKAS
EVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEM
QAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVE
AVSLGVPHEVAEGATCQAYELADYSNLRETDI
|
|
|
|---|
| BDBM50204306 |
|---|
| n/a |
|---|
| Name | BDBM50204306 |
|---|
| Synonyms: | CHEMBL3897499 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H31F3N2 |
|---|
| Mol. Mass. | 416.5222 |
|---|
| SMILES | [H][C@@]12CCC[C@@]3([H])N(CCC)CC[C@@]([H])(c4cc5ccc(cc5nc4[C@@H]1CC)C(F)(F)F)[C@]23[H] |r| |
|---|
| Structure | 
|
|---|
Search and Browse
