| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-7 |
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| Ligand | BDBM50205620 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1628501 (CHEMBL3871086) |
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| IC50 | 249000±n/a nM |
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| Citation |  Barros, TG; Santos, JAN; de Souza, BEG; Sodero, ACR; de Souza, AMT; da Silva, DP; Rodrigues, CR; Pinheiro, S; Dias, LRS; Abrahim-Vieira, B; Puzer, L; Muri, EMF Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor. Bioorg Med Chem Lett27:314-318 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-7 |
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| Name: | Kallikrein-7 |
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| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27535.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469257 |
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| Residue: | 253 |
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| Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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| BDBM50205620 |
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| n/a |
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| Name | BDBM50205620 |
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| Synonyms: | CHEMBL3943212 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H40N2O6 |
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| Mol. Mass. | 536.6591 |
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| SMILES | [H][C@]12OC[C@H](N(C(=O)Cc3ccc(O)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r| |
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| Structure | 
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