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TargetMacrophage migration inhibitory factor
LigandBDBM50206062
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1628621 (CHEMBL3871206)
Ki 37±n/a nM
Citation Cisneros, JARobertson, MJMercado, BQJorgensen, WL Systematic Study of Effects of Structural Modifications on the Aqueous Solubility of Drug-like Molecules. ACS Med Chem Lett8:124-127 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Macrophage migration inhibitory factor
Name:Macrophage migration inhibitory factor
Synonyms:GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:Enzyme
Mol. Mass.:12478.18
Organism:Homo sapiens (Human)
Description:P14174
Residue:115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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  Blast E-value cutoff:
BDBM50206062
n/a
NameBDBM50206062
Synonyms:CHEMBL3890541 | US10968198, Example 44
TypeSmall organic molecule
Emp. Form.C21H17FN4O5
Mol. Mass.424.3819
SMILESOC(=O)COCCOc1ccc2nc(ccc2c1)-c1cn(nn1)-c1ccc(O)c(F)c1
Structure
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