Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMacrophage migration inhibitory factor
LigandBDBM50167985
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1628621 (CHEMBL3871206)
Ki 161±n/a nM
Citation Cisneros, JARobertson, MJMercado, BQJorgensen, WL Systematic Study of Effects of Structural Modifications on the Aqueous Solubility of Drug-like Molecules. ACS Med Chem Lett8:124-127 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Macrophage migration inhibitory factor
Name:Macrophage migration inhibitory factor
Synonyms:GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:Enzyme
Mol. Mass.:12478.18
Organism:Homo sapiens (Human)
Description:P14174
Residue:115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50167985
n/a
NameBDBM50167985
Synonyms:CHEMBL3798384 | US10336721, Example 21 | US10968198, Example 21
TypeSmall organic molecule
Emp. Form.C25H27N5O4
Mol. Mass.461.513
SMILESOc1ccc(cc1)-n1cc(nn1)-c1ccc2cc(OCCOCCN3CCOCC3)ccc2n1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: