| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
|---|
| Ligand | BDBM50206788 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1629238 (CHEMBL3871864) |
|---|
| Ki | 0.890000±n/a nM |
|---|
| Citation |  Yoshinaga, H; Masumoto, S; Koyama, K; Kinomura, N; Matsumoto, Y; Kato, T; Baba, S; Matsumoto, K; Horisawa, T; Oki, H; Yabuuchi, K; Kodo, T Discovery of SMP-304, a novel benzylpiperidine derivative with serotonin transporter inhibitory activity and 5-HT Bioorg Med Chem25:293-304 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1A |
|---|
| Name: | 5-hydroxytryptamine receptor 1A |
|---|
| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46122.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 422 |
|---|
| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
|
|
|
|---|
| BDBM50206788 |
|---|
| n/a |
|---|
| Name | BDBM50206788 |
|---|
| Synonyms: | CHEMBL3949638 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H28BrNO |
|---|
| Mol. Mass. | 438.4 |
|---|
| SMILES | COc1ccc(Br)c(CC2CCN(CCc3ccc4ccccc4c3)CC2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
