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TargetAmine oxidase [flavin-containing] B
LigandBDBM50172756
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1629362 (CHEMBL3871988)
IC50 195±n/a nM
Citation Ko?ak, U; Knez, D; Coquelle, N; Brus, B; Pi?lar, A; Nachon, F; Brazzolotto, X; Kos, J; Colletier, JP; Gobec, S N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents. Bioorg Med Chem25:633-645 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:Protein
Mol. Mass.:58768.76
Organism:Homo sapiens (Human)
Description:P27338
Residue:520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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BDBM50172756
n/a
NameBDBM50172756
Synonyms:Benzyl-methyl-prop-2-ynyl-amine | CHEMBL673 | Eutonyl | Eutron | N-benzyl-N-methylprop-2-yn-1-amine | PARGYLINE | US9603833, Pargyline
TypeSmall organic molecule
Emp. Form.C11H13N
Mol. Mass.159.2276
SMILESCN(CC#C)Cc1ccccc1
Structure
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