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Target5-hydroxytryptamine receptor 6
LigandBDBM50207037
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1629512 (CHEMBL3872138)
Ki 50±n/a nM
Citation Saavedra, OMKarila, DBrossard, DRojas, ADupuis, DGohier, AMannoury la Cour, CMillan, MJOrtuno, JCHanessian, S Design and synthesis of novel N-sulfonyl-2-indoles that behave as 5-HT Bioorg Med Chem25:38-52 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 6
Name:5-hydroxytryptamine receptor 6
Synonyms:5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:46968.43
Organism:Homo sapiens (Human)
Description:P50406
Residue:440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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BDBM50207037
n/a
NameBDBM50207037
Synonyms:CHEMBL3889852
TypeSmall organic molecule
Emp. Form.C20H20N2O2S
Mol. Mass.352.45
SMILES[H][C@]12CCNCC[C@@]1([H])c1c2ccc2n(ccc12)S(=O)(=O)c1ccccc1 |r|
Structure
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