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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(3) dopamine receptor | ||
| Ligand | BDBM50207146 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1630050 (CHEMBL3872756) | ||
| Ki | 0.190000±n/a nM | ||
| Citation |  Chen, XW; Sun, YY; Fu, L; Li, JQ Synthesis and pharmacological characterization of novel N-(trans-4-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)cyclohexyl)amides as potential multireceptor atypical antipsychotics. Eur J Med Chem123:332-353 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(3) dopamine receptor | |||
| Name: | D(3) dopamine receptor | ||
| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 | ||
| Type: | n/a | ||
| Mol. Mass.: | 44243.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 400 | ||
| Sequence: |
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| BDBM50207146 | |||
| n/a | |||
| Name | BDBM50207146 | ||
| Synonyms: | CHEMBL3929168 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H38N4OS | ||
| Mol. Mass. | 454.671 | ||
| SMILES | O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)C1CCCCC1 |r,wU:3.2,wD:6.6,(15.11,-24.25,;14.71,-22.76,;15.73,-21.63,;17.27,-21.94,;18.29,-20.81,;19.78,-21.12,;20.25,-22.56,;21.78,-22.92,;22.81,-21.74,;24.3,-22.1,;24.76,-23.53,;26.3,-23.84,;27.33,-22.71,;26.81,-21.28,;25.32,-20.92,;28.82,-23.02,;29.43,-24.46,;30.97,-24.31,;31.28,-22.76,;32.56,-22,;32.56,-20.45,;31.28,-19.69,;29.94,-20.45,;29.94,-22,;19.22,-23.74,;17.73,-23.43,;13.21,-22.35,;12.8,-20.86,;11.31,-20.51,;10.23,-21.59,;10.64,-23.07,;12.13,-23.48,)| | ||
| Structure | 
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