| Reaction Details |
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 | Report a problem with these data |
| Target | Pancreatic triacylglycerol lipase |
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| Ligand | BDBM50207370 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1631102 |
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| IC50 | 9580±n/a nM |
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| Citation |  Sridhar, SN; Ginson, G; Venkataramana Reddy, PO; Tantak, MP; Kumar, D; Paul, AT Synthesis, evaluation and molecular modelling studies of 2-(carbazol-3-yl)-2-oxoacetamide analogues as a new class of potential pancreatic lipase inhibitors. Bioorg Med Chem25:609-620 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pancreatic triacylglycerol lipase |
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| Name: | Pancreatic triacylglycerol lipase |
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| Synonyms: | LIPP_PIG | PL | PNLIP | PTL | Pancreatic lipase | Pancreatic triacylglycerol lipase |
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| Type: | Enzyme |
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| Mol. Mass.: | 50080.69 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P00591 |
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| Residue: | 450 |
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| Sequence: | SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTI
TNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQ
NIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAE
PCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQK
NILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPC
PSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSL
FGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASK
ITVERNDGKVYDFCSQETVREEVLLTLNPC
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| BDBM50207370 |
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| n/a |
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| Name | BDBM50207370 |
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| Synonyms: | CHEMBL3896540 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H20N2O5 |
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| Mol. Mass. | 404.4153 |
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| SMILES | COc1cc(NC(=O)C(=O)c2ccc3[nH]c4ccccc4c3c2)cc(OC)c1OC |
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| Structure | 
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