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TargetPancreatic lipase
LigandBDBM50207383
Substrate/Competitorn/a
Meas. Tech.ChEBML_1631109
IC50 428600±n/a nM
Citation Sridhar SNGinson GVenkataramana Reddy POTantak MPKumar DPaul AT Synthesis, evaluation and molecular modelling studies of 2-(carbazol-3-yl)-2-oxoacetamide analogues as a new class of potential pancreatic lipase inhibitors. Bioorg Med Chem 25:609-620 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Pancreatic lipase
Name:Pancreatic lipase
Synonyms:PL
Type:PROTEIN
Mol. Mass.:51157.75
Organism:Homo sapiens (Human)
Description:ChEMBL_527250
Residue:465
Sequence:
MLPLWTLSLLLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTN
ENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNCIC
VDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGR
RTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGH
LDFFPNGGVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGF
PCASYNVFTANKCFPCPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVS
VTLSGKKVTGHILVSLFGNKGNSKQYEIFKGTLKPDSTHSNEFDSDVDVGDLQMVKFIWY
NNVINPTLPRVGASKIIVETNVGKQFNFCSPETVREEVLLTLTPC
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  Blast E-value cutoff:
BDBM50207383
n/a
NameBDBM50207383
Synonyms:CHEMBL3893262
TypeSmall organic molecule
Emp. Form.C20H21NO3
Mol. Mass.323.3856
SMILESCOc1cc2[nH]c3c4C=CC(C)(C)Oc4c(C)cc3c2cc1OC |c:8|
Structure
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