| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50208254 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1632480 (CHEMBL3875272) |
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| Ki | 4.0±n/a nM |
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| Citation |  Wieckowska, A; Kolaczkowski, M; Bucki, A; Godyn, J; Marcinkowska, M; Wieckowski, K; Zareba, P; Siwek, A; Kazek, G; Gluch-Lutwin, M; Mierzejewski, P; Bienkowski, P; Sienkiewicz-Jarosz, H; Knez, D; Wichur, T; Gobec, S; Malawska, B Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT Eur J Med Chem124:63-81 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50208254 |
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| n/a |
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| Name | BDBM50208254 |
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| Synonyms: | CHEMBL3883921 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H36N4O2S |
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| Mol. Mass. | 516.697 |
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| SMILES | CN(CCCCN1CCN(CC1)c1cccc2n(ccc12)S(=O)(=O)c1ccccc1)Cc1ccccc1 |
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| Structure | 
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