| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK2 |
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| Ligand | BDBM50208635 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1633067 (CHEMBL3875859) |
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| IC50 | 80±n/a nM |
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| Citation |  Labrière, C; Lozach, O; Blairvacq, M; Meijer, L; Guillou, C Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors. Eur J Med Chem124:920-934 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein kinase CLK2 |
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| Name: | Dual specificity protein kinase CLK2 |
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| Synonyms: | 2.7.12.1 | CDC-like kinase 2 | CDC-like kinase 2 (CLK2) | CDC2-like kinase 2 (CLK2) | CLK2 | CLK2_HUMAN |
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| Type: | n/a |
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| Mol. Mass.: | 60128.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49760 |
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| Residue: | 499 |
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| Sequence: | MPHPRRYHSSERGSRGSYREHYRSRKHKRRRSRSWSSSSDRTRRRRREDSYHVRSRSSYD
DRSSDRRVYDRRYCGSYRRNDYSRDRGDAYYDTDYRHSYEYQRENSSYRSQRSSRRKHRR
RRRRSRTFSRSSSQHSSRRAKSVEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQC
VDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMC
ISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVN
SDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQ
PCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLD
WDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFA
RLRAEPPNKLWDSSRDISR
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| BDBM50208635 |
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| n/a |
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| Name | BDBM50208635 |
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| Synonyms: | CHEMBL3883660 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H11N3O |
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| Mol. Mass. | 273.2887 |
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| SMILES | COc1ccc2c(c1)[nH]c1c2c(cc2cnccc12)C#N |
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| Structure | 
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