| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 26 |
|---|
| Ligand | BDBM50208911 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1633294 (CHEMBL3876086) |
|---|
| IC50 | 2220±n/a nM |
|---|
| Citation |  Katz, JD; Haidle, A; Childers, KK; Zabierek, AA; Jewell, JP; Hou, Y; Altman, MD; Szewczak, A; Chen, D; Harsch, A; Hayashi, M; Warren, L; Hutton, M; Nuthall, H; Su, HP; Munshi, S; Stanton, MG; Davies, IW; Munoz, B; Northrup, A Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors. Bioorg Med Chem Lett27:114-120 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase 26 |
|---|
| Name: | Serine/threonine-protein kinase 26 |
|---|
| Synonyms: | MASK | MST4 | STK26 | STK26_HUMAN | Serine/threonine-protein kinase MST4 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 46517.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1510631 |
|---|
| Residue: | 416 |
|---|
| Sequence: | MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEA
EDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQ
IATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV
GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLV
GDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHS
DDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQTLSCLSMIITPA
FAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQKCSADESP
|
|
|
|---|
| BDBM50208911 |
|---|
| n/a |
|---|
| Name | BDBM50208911 |
|---|
| Synonyms: | CHEMBL3884319 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H22N4O2 |
|---|
| Mol. Mass. | 386.4464 |
|---|
| SMILES | CC1(C)C(=O)N([C@H]2CCc3c2cccc3O)c2nc(Nc3ccccc3)ncc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
