| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50103595 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1633572 (CHEMBL3876364) |
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| IC50 | 1000±n/a nM |
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| Citation |  Gunia-Krzyzak, A; Zelaszczyk, D; Rapacz, A; Zeslawska, E; Waszkielewicz, AM; Panczyk, K; Sloczynska, K; Pekala, E; Nitek, W; Filipek, B; Marona, H Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH Bioorg Med Chem25:471-482 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40115.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 359 |
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| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
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| BDBM50103595 |
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| n/a |
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| Name | BDBM50103595 |
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| Synonyms: | Brumetadina | CHEBI:3699 | Cimetidine | Tagamet | Tagamet HB | Tagamet HB 200 | Valmagen |
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| Type | Small organic molecule |
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| Emp. Form. | C10H16N6S |
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| Mol. Mass. | 252.339 |
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| SMILES | CN\C(NC#N)=N/CCSCc1nc[nH]c1C |
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| Structure | 
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