| Reaction Details |
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 | Report a problem with these data |
| Target | REST corepressor 1 [4-485] |
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| Ligand | BDBM50158884 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1634253 (CHEMBL3877045) |
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| Ki | 140±n/a nM |
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| Citation |  Amano, Y; Umezawa, N; Sato, S; Watanabe, H; Umehara, T; Higuchi, T Activation of lysine-specific demethylase 1 inhibitor peptide by redox-controlled cleavage of a traceless linker. Bioorg Med Chem25:1227-1234 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| REST corepressor 1 [4-485] |
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| Name: | REST corepressor 1 [4-485] |
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| Synonyms: | KIAA0071 | Protein CoREST | RCOR | RCOR1 | RCOR1_HUMAN | REST corepressor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53029.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108118 |
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| Residue: | 482 |
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| Sequence: | MVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAASAAA
APNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKL
ARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLA
DLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKT
SVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHST
QAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALK
EKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNF
FVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVRYAS
AS
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| BDBM50158884 |
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| n/a |
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| Name | BDBM50158884 |
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| Synonyms: | CHEMBL3785550 |
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| Type | Small organic molecule |
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| Emp. Form. | C51H87N17O10 |
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| Mol. Mass. | 1098.3444 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(N)=O |r| |
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| Structure | 
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