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TargetBcl-2-related protein A1
LigandBDBM50210070
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1634279
Ki<0.100000±n/a nM
Citation de Araujo ADLim JGood ACSkerlj RTFairlie DP Electrophilic Helical Peptides That Bond Covalently, Irreversibly, and Selectively in a Protein-Protein Interaction Site. ACS Med Chem Lett 8:22-26 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bcl-2-related protein A1
Name:Bcl-2-related protein A1
Synonyms:Bcl-2-like protein 5 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:Apoptosis regulator protein
Mol. Mass.:20130.01
Organism:Homo sapiens (Human)
Description:n/a
Residue:175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVN
VVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISY
FVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50210070
n/a
NameBDBM50210070
Synonyms:CHEMBL3883565
TypeSmall organic molecule
Emp. Form.C120H186N34O31
Mol. Mass.2600.97
SMILESCC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CNC(=O)C=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@]1(C)CCCC=CCCC[C@](C)(NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](NC1=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
Structure
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