| Reaction Details |
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 | Report a problem with these data |
| Target | Oxidized purine nucleoside triphosphate hydrolase |
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| Ligand | BDBM50152124 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1634433 (CHEMBL3877225) |
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| IC50 | 5.0±n/a nM |
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| Citation |  Munoz, L Non-kinase targets of protein kinase inhibitors. Nat Rev Drug Discov16:424-440 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxidized purine nucleoside triphosphate hydrolase |
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| Name: | Oxidized purine nucleoside triphosphate hydrolase |
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| Synonyms: | 7,8-dihydro-8-oxoguanine triphosphatase | 8ODP_HUMAN | MTH1 | MutT homolog 1 protein (MTH1) | NUDT1 |
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| Type: | Protein |
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| Mol. Mass.: | 22514.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P36639 |
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| Residue: | 197 |
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| Sequence: | MYWSNQITRRLGERVQGFMSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVL
LGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPE
LMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKF
QGQDTILDYTLREVDTV
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| BDBM50152124 |
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| n/a |
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| Name | BDBM50152124 |
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| Synonyms: | CHEMBL3782004 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12Cl2N4 |
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| Mol. Mass. | 295.167 |
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| SMILES | Nc1nc(NC2CC2)cc(n1)-c1cccc(Cl)c1Cl |
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| Structure | 
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