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TargetOxidized purine nucleoside triphosphate hydrolase
LigandBDBM50210165
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1634434 (CHEMBL3877226)
IC50 100±n/a nM
Citation Munoz, L Non-kinase targets of protein kinase inhibitors. Nat Rev Drug Discov16:424-440 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Oxidized purine nucleoside triphosphate hydrolase
Name:Oxidized purine nucleoside triphosphate hydrolase
Synonyms:7,8-dihydro-8-oxoguanine triphosphatase | 8ODP_HUMAN | MTH1 | MutT homolog 1 protein (MTH1) | NUDT1
Type:Protein
Mol. Mass.:22514.81
Organism:Homo sapiens (Human)
Description:P36639
Residue:197
Sequence:
MYWSNQITRRLGERVQGFMSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVL
LGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPE
LMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKF
QGQDTILDYTLREVDTV
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BDBM50210165
n/a
NameBDBM50210165
Synonyms:CHEMBL1709874
TypeSmall organic molecule
Emp. Form.C13H14N6
Mol. Mass.254.2905
SMILESNc1nc(NCCc2ccccc2)c2nc[nH]c2n1
Structure
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