| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 1B1 |
|---|
| Ligand | BDBM50014323 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1634976 (CHEMBL3877874) |
|---|
| IC50 | 300±n/a nM |
|---|
| Citation |  Poirier, D; Roy, J; Cortés-Benítez, F; Dutour, R Targeting cytochrome P450 (CYP) 1B1 with steroid derivatives. Bioorg Med Chem Lett26:5272-5276 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 1B1 |
|---|
| Name: | Cytochrome P450 1B1 |
|---|
| Synonyms: | CP1B1_HUMAN | CYP1B1 | CYPIB1 | Cytochrome P450 1B1 (CYP1B1) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60861.81 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1474523 |
|---|
| Residue: | 543 |
|---|
| Sequence: | MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRRRQLRSAPPGPFAWPLI
GNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPAF
ASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVAL
LVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSL
VDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFILSA
EKKAAGDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAEL
DQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVV
FVNQWSVNHDPLKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQL
FLFISILAHQCDFRANPNEPAKMNFSYGLTIKPKSFKVNVTLRESMELLDSAVQNLQAKE
TCQ
|
|
|
|---|
| BDBM50014323 |
|---|
| n/a |
|---|
| Name | BDBM50014323 |
|---|
| Synonyms: | 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo[h]chromen-4-one | 7,8-Benzoflavone | CHEMBL283196 | alpha-naphthoflavone |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H12O2 |
|---|
| Mol. Mass. | 272.2974 |
|---|
| SMILES | O=c1cc(oc2c3ccccc3ccc12)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
