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TargetTranslocator protein
LigandBDBM22032
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1635860
IC50 1.1±n/a nM
Citation Kim TYang HYPark BGJung SYPark JHPark KDMin SJTae JYang HCho SCho SJSong HMook-Jung ILee JPae AN Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease. Eur J Med Chem 125:1172-1192 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Translocator protein
Name:Translocator protein
Synonyms:Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor
Type:Enzyme
Mol. Mass.:18834.74
Organism:Homo sapiens (Human)
Description:P30536
Residue:169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
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  Blast E-value cutoff:
BDBM22032
n/a
NameBDBM22032
Synonyms:1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoquinoline-3-carboxamide | CHEMBL15313 | N-(butan-2-yl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide | PK 11195 | PK-11195 | PK11195 | RP 52028 | [3H]PK 11195
Typeradiolabeled ligand
Emp. Form.C21H21ClN2O
Mol. Mass.352.857
SMILESCCC(C)N(C)C(=O)c1cc2ccccc2c(n1)-c1ccccc1Cl
Structure
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