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TargetTranslocator protein
LigandBDBM50185957
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1635860
IC50 0.920000±n/a nM
Citation Kim TYang HYPark BGJung SYPark JHPark KDMin SJTae JYang HCho SCho SJSong HMook-Jung ILee JPae AN Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease. Eur J Med Chem 125:1172-1192 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Translocator protein
Name:Translocator protein
Synonyms:Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor
Type:Enzyme
Mol. Mass.:18834.74
Organism:Homo sapiens (Human)
Description:P30536
Residue:169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
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  Blast E-value cutoff:
BDBM50185957
n/a
NameBDBM50185957
Synonyms:CHEMBL205767 | N-(2-isopropoxybenzyl)-N-(4-chloro-2-phenoxyphenyl)acetamide | N-(4-chloro-2-phenoxyphenyl)-N-(2-isopropoxybenzyl)acetamide
TypeSmall organic molecule
Emp. Form.C24H24ClNO3
Mol. Mass.409.905
SMILESCC(C)Oc1ccccc1CN(C(C)=O)c1ccc(Cl)cc1Oc1ccccc1
Structure
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