| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acyl-protein thioesterase 2 |
|---|
| Ligand | BDBM50212216 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1636766 (CHEMBL3879664) |
|---|
| Ki | 1100±n/a nM |
|---|
| Citation |  Won, SJ; Eschweiler, JD; Majmudar, JD; Chong, FS; Hwang, SY; Ruotolo, BT; Martin, BR Affinity-Based Selectivity Profiling of an In-Class Selective Competitive Inhibitor of Acyl Protein Thioesterase 2. ACS Med Chem Lett8:215-220 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Acyl-protein thioesterase 2 |
|---|
| Name: | Acyl-protein thioesterase 2 |
|---|
| Synonyms: | APT2 | Acyl-protein thioesterase 2 (APT2 WT) | LYPA2_HUMAN | LYPLA2 | Lysophospholipase II |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 24740.23 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O95372 |
|---|
| Residue: | 231 |
|---|
| Sequence: | MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAP
RIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGG
FSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVP
VRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV
|
|
|
|---|
| BDBM50212216 |
|---|
| n/a |
|---|
| Name | BDBM50212216 |
|---|
| Synonyms: | CHEMBL3944678 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C43H54N8O9S3 |
|---|
| Mol. Mass. | 923.132 |
|---|
| SMILES | [H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCn3cc(COc4ccc(cc4)N4CCN(CC4)C(=O)c4cc5CS(=O)(=O)c6ccccc6-c5s4)nn3)[C@@]1([H])NC(=O)N2 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
