| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50213878 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_85064 |
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| IC50 | 684±n/a nM |
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| Citation |  TBA Bioorg Med Chem Lett6:1795-1798 (1996) |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_CAVPO | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40567.22 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | For the H2 receptor-binding assays, guinea pig striatum was used. |
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| Residue: | 359 |
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| Sequence: | MAFNGTVPSFCMDFTVYKVTISVILIILILVTVAGNVVVCLAVGLNRRLRSLTNCFIVSL
AVTDLLLGLLVLPFSAIYQLSCKWSFSKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLITPARVAISLVFIWVISITLSFLSIHLGWNSRNETSKDNDTIVKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYFRIFKIAREQARRINHIGSWKAATIREHKATVTLAAVM
GAFIICWFPYFTVFVYRGLKGDDAVNEVFEDVVLWLGYANSALNPILYAALNRDFRTAYH
QLFCCRLASHNSHETSLRLNNSQLNRSQCQEPRWQEDKPLNLQVWSGTEVTAPQGATNR
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|
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| BDBM50213878 |
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| n/a |
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| Name | BDBM50213878 |
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| Synonyms: | CHEMBL301294 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19N3O3S |
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| Mol. Mass. | 321.395 |
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| SMILES | CN(C)Cc1cc(OC\C=C/CN=c2c(O)c(O)c2=N)cs1 |
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| Structure | 
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