| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50217228 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1978 (CHEMBL617583) |
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| Ki | 158±n/a nM |
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| Citation |  Chan, WN; Evans, JM; Hadley, MS; Herdon, HJ; Jerman, JC; Parsons, AA; Read, SJ; Stean, TO; Thompson, M; Upton, N Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)- 3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent. Bioorg Med Chem Lett9:285-90 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT-1D | 5-HT1D | 5-hydroxytryptamine receptor 1D | 5HT1D_RAT | Htr1d | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1D |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41551.75 |
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| Organism: | RAT |
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| Description: | 5-HT1D HTR1D RAT::P28565 |
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| Residue: | 374 |
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| Sequence: | MSLPNQSLEGLPQEASNRSLNATGAWDPEVLQALRISLVVVLSIITLATVLSNAFVLTTI
LLTKKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCT
ASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAAVWAISICISIPPLFWRQATAHE
EMSDCLVNTSQISYTIYSTCGAFYIPSILLIILYGRIYVAARSRILNPPSLYGKRFTTAQ
LITGSAGSSLCSLNPSLHESHTHTVGSPLFFNQVKIKLADSILERKRISAARERKATKTL
GIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPVIYTVFNEDF
RQAFQRVVHFRKAS
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| BDBM50217228 |
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| n/a |
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| Name | BDBM50217228 |
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| Synonyms: | CHEMBL98195 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19NO4S |
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| Mol. Mass. | 345.413 |
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| SMILES | CC(=O)c1ccc2OC(C)(C)[C@H](O)[C@@H](NC(=O)c3ccsc3)c2c1 |
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| Structure | 
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