| Reaction Details |
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 | Report a problem with these data |
| Target | Penicillin-binding protein 2 |
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| Ligand | BDBM50218764 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_153656 (CHEMBL762721) |
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| IC50 | >545000±n/a nM |
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| Citation |  Chen, Z; Demuth, TP; Wireko, FC Stereoselective synthesis and antibacterial evaluation of 4-amido-isothiazolidinone oxides. Bioorg Med Chem Lett11:2111-5 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Penicillin-binding protein 2 |
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| Name: | Penicillin-binding protein 2 |
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| Synonyms: | Penicillin-binding protein | Penicillin-binding protein 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 79295.25 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_153530 |
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| Residue: | 716 |
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| Sequence: | MTENKGSSQPKKNGNNGGKSNSKKNRNVKRTIIKIIGFMIIAFFVVLLLGILLFAYYAWK
APAFTEAKLQDPIPAKIYDKNGELVKTLDNGQRHEHVNLKDVPKSMKDAVLATEDNRFYE
HGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQ
EYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIY
DHPKAAEDRKNTVLYLMHYHKRITDKQWEDAKKIDLKANLVNRTAEERQNIDTNQDSEYN
SYVNFVKSELMNNKAFKDENLGNVLQSGIKIYTNMDKDVQKTLQNDVDNGSFYKNKDQQV
GATILDSKTGGLVAISGGRDFKDVVNRNQATDPHPTGSSLKPFLAYGPAIENMKWATNHA
IQDESSYQVDGSTFRNYDTKSHGTVSIYDALRQSFNIPALKAWQSVKQNAGNDAPKKFAA
KLGLNYEGDIGPSEVLGGSASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIEY
DHTSHKAMSDYTAYMLAEMLKGTFKPYGSAYGHGVSGVNMGAKTGTGTYGAETYSQYNLP
DNAAKDVWINGFTPQYTMSVWMGFSKVKQYGENSFVGHSQQEYPQFLYENVMSKISSRDG
EDFKRPSSVSGSIPSINVSGSQDNNTTNRSTHGGSDTSANSSGTAQSNNNTRSQQS
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| BDBM50218764 |
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| n/a |
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| Name | BDBM50218764 |
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| Synonyms: | CHEMBL67669 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26N2O6S |
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| Mol. Mass. | 458.527 |
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| SMILES | CC(C)[C@@H](N1[S+]([O-])C[C@H](NC(=O)COc2ccccc2)C1=O)C(=O)OCc1ccccc1 |r| |
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| Structure | 
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