| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Penicillin-binding protein 2 |
|---|
| Ligand | BDBM50218765 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_153656 (CHEMBL762721) |
|---|
| IC50 | >663000±n/a nM |
|---|
| Citation |  Chen, Z; Demuth, TP; Wireko, FC Stereoselective synthesis and antibacterial evaluation of 4-amido-isothiazolidinone oxides. Bioorg Med Chem Lett11:2111-5 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Penicillin-binding protein 2 |
|---|
| Name: | Penicillin-binding protein 2 |
|---|
| Synonyms: | Penicillin-binding protein | Penicillin-binding protein 2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 79295.25 |
|---|
| Organism: | Staphylococcus aureus |
|---|
| Description: | ChEMBL_153530 |
|---|
| Residue: | 716 |
|---|
| Sequence: | MTENKGSSQPKKNGNNGGKSNSKKNRNVKRTIIKIIGFMIIAFFVVLLLGILLFAYYAWK
APAFTEAKLQDPIPAKIYDKNGELVKTLDNGQRHEHVNLKDVPKSMKDAVLATEDNRFYE
HGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQ
EYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIY
DHPKAAEDRKNTVLYLMHYHKRITDKQWEDAKKIDLKANLVNRTAEERQNIDTNQDSEYN
SYVNFVKSELMNNKAFKDENLGNVLQSGIKIYTNMDKDVQKTLQNDVDNGSFYKNKDQQV
GATILDSKTGGLVAISGGRDFKDVVNRNQATDPHPTGSSLKPFLAYGPAIENMKWATNHA
IQDESSYQVDGSTFRNYDTKSHGTVSIYDALRQSFNIPALKAWQSVKQNAGNDAPKKFAA
KLGLNYEGDIGPSEVLGGSASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIEY
DHTSHKAMSDYTAYMLAEMLKGTFKPYGSAYGHGVSGVNMGAKTGTGTYGAETYSQYNLP
DNAAKDVWINGFTPQYTMSVWMGFSKVKQYGENSFVGHSQQEYPQFLYENVMSKISSRDG
EDFKRPSSVSGSIPSINVSGSQDNNTTNRSTHGGSDTSANSSGTAQSNNNTRSQQS
|
|
|
|---|
| BDBM50218765 |
|---|
| n/a |
|---|
| Name | BDBM50218765 |
|---|
| Synonyms: | CHEMBL66962 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H13ClN2O7S |
|---|
| Mol. Mass. | 376.77 |
|---|
| SMILES | CC(N1C(=O)C(CS1(=O)=O)NC(=O)Oc1ccc(Cl)cc1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
