| Reaction Details |
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 | Report a problem with these data |
| Target | Penicillin-binding protein 2 |
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| Ligand | BDBM50218771 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_153656 (CHEMBL762721) |
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| IC50 | >552000±n/a nM |
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| Citation |  Chen, Z; Demuth, TP; Wireko, FC Stereoselective synthesis and antibacterial evaluation of 4-amido-isothiazolidinone oxides. Bioorg Med Chem Lett11:2111-5 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Penicillin-binding protein 2 |
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| Name: | Penicillin-binding protein 2 |
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| Synonyms: | Penicillin-binding protein | Penicillin-binding protein 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 79295.25 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_153530 |
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| Residue: | 716 |
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| Sequence: | MTENKGSSQPKKNGNNGGKSNSKKNRNVKRTIIKIIGFMIIAFFVVLLLGILLFAYYAWK
APAFTEAKLQDPIPAKIYDKNGELVKTLDNGQRHEHVNLKDVPKSMKDAVLATEDNRFYE
HGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQ
EYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIY
DHPKAAEDRKNTVLYLMHYHKRITDKQWEDAKKIDLKANLVNRTAEERQNIDTNQDSEYN
SYVNFVKSELMNNKAFKDENLGNVLQSGIKIYTNMDKDVQKTLQNDVDNGSFYKNKDQQV
GATILDSKTGGLVAISGGRDFKDVVNRNQATDPHPTGSSLKPFLAYGPAIENMKWATNHA
IQDESSYQVDGSTFRNYDTKSHGTVSIYDALRQSFNIPALKAWQSVKQNAGNDAPKKFAA
KLGLNYEGDIGPSEVLGGSASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIEY
DHTSHKAMSDYTAYMLAEMLKGTFKPYGSAYGHGVSGVNMGAKTGTGTYGAETYSQYNLP
DNAAKDVWINGFTPQYTMSVWMGFSKVKQYGENSFVGHSQQEYPQFLYENVMSKISSRDG
EDFKRPSSVSGSIPSINVSGSQDNNTTNRSTHGGSDTSANSSGTAQSNNNTRSQQS
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| BDBM50218771 |
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| n/a |
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| Name | BDBM50218771 |
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| Synonyms: | CHEMBL63749 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17ClN2O7S |
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| Mol. Mass. | 452.865 |
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| SMILES | Clc1ccc(OC(=O)NC2CS(=O)(=O)N(CC(=O)OCc3ccccc3)C2=O)cc1 |
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| Structure | 
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