| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50219985 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_200646 (CHEMBL802980) |
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| IC50 | 37.1±n/a nM |
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| Citation |  Honda, T; Masuda, T; Yoshida, S; Arai, M; Kobayashi, Y; Yamashita, M Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives. Bioorg Med Chem Lett12:1921-4 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | Influenza A Virus Neuraminidase | NA | NRAM_I34A1 | Neuraminidase | Neuraminidase A |
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| Type: | Enzyme |
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| Mol. Mass.: | 50124.14 |
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| Organism: | Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) |
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| Description: | P03468 |
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| Residue: | 454 |
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| Sequence: | MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNST
WVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLT
QGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGI
SGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKI
FKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIG
YICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIW
DPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKT
IWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
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| BDBM50219985 |
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| n/a |
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| Name | BDBM50219985 |
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| Synonyms: | CHEMBL56107 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24F3N5O9 |
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| Mol. Mass. | 487.3851 |
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| SMILES | [#8]-[#6](=O)C(F)(F)F.[H][C@@]([#7]-[#6](-[#6])=O)([#6@H](-[#8])-[#6]-[#8])[C@]1([H])[#8]-[#6](=[#6]-[#6@H](\[#7]=[#6](/[#7])-[#7])-[#6@H]1-[#7]-[#6](-[#6])=O)-[#6](-[#8])=O |c:19| |
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| Structure | 
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