| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuraminidase |
|---|
| Ligand | BDBM50219998 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_200640 (CHEMBL802974) |
|---|
| IC50 | 67.5±n/a nM |
|---|
| Citation |  Honda, T; Masuda, T; Yoshida, S; Arai, M; Kaneko, S; Yamashita, M Synthesis and anti-influenza virus activity of 7-O-alkylated derivatives related to zanamivir. Bioorg Med Chem Lett12:1925-8 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuraminidase |
|---|
| Name: | Neuraminidase |
|---|
| Synonyms: | Influenza A Virus Neuraminidase | NA | NRAM_I34A1 | Neuraminidase | Neuraminidase A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 50124.14 |
|---|
| Organism: | Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) |
|---|
| Description: | P03468 |
|---|
| Residue: | 454 |
|---|
| Sequence: | MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNST
WVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLT
QGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGI
SGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKI
FKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIG
YICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIW
DPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKT
IWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
|
|
|
|---|
| BDBM50219998 |
|---|
| n/a |
|---|
| Name | BDBM50219998 |
|---|
| Synonyms: | CHEMBL291455 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H33F3N4O9 |
|---|
| Mol. Mass. | 542.5033 |
|---|
| SMILES | OC(=O)C(F)(F)F.[H][C@]1(OC(=C[C@H](NC(N)=N)[C@H]1NC(C)=O)C(O)=O)[C@H](OCC1CCCCC1)[C@H](O)CO |c:9| |
|---|
| Structure | 
|
|---|
Search and Browse
