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TargetHistamine H3 receptor
LigandBDBM50217149
Substrate/Competitorn/a
Meas. Tech.ChEMBL_86929
Ki 23±n/a nM
Citation Faghih RDwight WVasudevan ADinges JConner SEEsbenshade TABennani YLHancock AA Aminoalkoxybiphenylnitriles as histamine-3 receptor ligands. Bioorg Med Chem Lett 12:3077-9 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Histamine H3 receptor
Name:Histamine H3 receptor
Synonyms:HH3R
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:48607.98
Organism:Rattus norvegicus (rat)
Description:n/a
Residue:445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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  Blast E-value cutoff:
BDBM50217149
n/a
NameBDBM50217149
Synonyms:CHEMBL102984
TypeSmall organic molecule
Emp. Form.C22H26N2O
Mol. Mass.334.4546
SMILESCC1CCCCN1CCCOc1ccc(cc1)-c1ccc(cc1)C#N
Structure
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