| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50217109 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_86929 (CHEMBL697538) |
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| Ki | 240±n/a nM |
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| Citation |  Faghih, R; Dwight, W; Vasudevan, A; Dinges, J; Conner, SE; Esbenshade, TA; Bennani, YL; Hancock, AA Aminoalkoxybiphenylnitriles as histamine-3 receptor ligands. Bioorg Med Chem Lett12:3077-9 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50217109 |
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| n/a |
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| Name | BDBM50217109 |
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| Synonyms: | CHEMBL446885 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27F3N2O4 |
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| Mol. Mass. | 452.4667 |
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| SMILES | CCOC(=O)N1CCN(CCCOc2ccc(cc2)-c2ccc(OC(F)(F)F)cc2)CC1 |
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| Structure | 
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