| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50217417 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_85805 (CHEMBL697083) |
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| Ki | 33884±n/a nM |
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| Citation |  Faghih, R; Dwight, W; Vasudevan, A; Dinges, J; Conner, SE; Esbenshade, TA; Bennani, YL; Hancock, AA Aminoalkoxybiphenylnitriles as histamine-3 receptor ligands. Bioorg Med Chem Lett12:3077-9 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40115.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 359 |
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| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
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| BDBM50217417 |
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| n/a |
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| Name | BDBM50217417 |
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| Synonyms: | CHEMBL102452 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25N3O |
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| Mol. Mass. | 335.4427 |
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| SMILES | NC1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)CC1 |
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| Structure | 
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