| Reaction Details |
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 | Report a problem with these data |
| Target | Tryptase delta |
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| Ligand | BDBM50217822 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_210701 (CHEMBL817298) |
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| IC50 | <1.7±n/a nM |
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| Citation |  Slusarchyk, WA; Bolton, SA; Hartl, KS; Huang, MH; Jacobs, G; Meng, W; Ogletree, ML; Pi, Z; Schumacher, WA; Seiler, SM; Sutton, JC; Treuner, U; Zahler, R; Zhao, G; Bisacchi, GS Synthesis of potent and highly selective inhibitors of human tryptase. Bioorg Med Chem Lett12:3235-8 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tryptase delta |
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| Name: | Tryptase delta |
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| Synonyms: | Delta-tryptase | HmMCP-3-like tryptase III | Mast cell mMCP-7-like | TPSD1 | TRYD_HUMAN | Tryptase delta | Tryptase-3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26578.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104777 |
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| Residue: | 242 |
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| Sequence: | MLLLAPQMLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGP
YWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQF
YIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPY
PLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVN
GT
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| BDBM50217822 |
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| n/a |
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| Name | BDBM50217822 |
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| Synonyms: | CHEMBL111173 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H39N7O5 |
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| Mol. Mass. | 541.6425 |
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| SMILES | NC(=N)N1CCCC(C[C@@H]2[C@H](N(C(=O)N3CCN(CC3)C(=O)NCCCCc3ccccc3)C2=O)C(O)=O)C1 |
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| Structure | 
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