| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50116963 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_3707 (CHEMBL875101) |
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| Ki | 2.1±n/a nM |
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| Citation |  Kikuchi, C; Suzuki, H; Hiranuma, T; Koyama, M New tetrahydrobenzindoles as potent and selective 5-HT(7) antagonists with increased In vitro metabolic stability. Bioorg Med Chem Lett13:61-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50116963 |
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| n/a |
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| Name | BDBM50116963 |
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| Synonyms: | 2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-2a,3,4,5-tetrahydrobenzo[cd]indol-2(1H)-one | 2a-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-2a,3,4,5-tetrahydro-1H-benzo[cd]indol-2-one | CHEMBL69257 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30N2O |
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| Mol. Mass. | 386.5292 |
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| SMILES | O=C1Nc2cccc3CCCC1(CCCCN1CCC(=CC1)c1ccccc1)c23 |c:20| |
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| Structure | 
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