| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase |
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| Ligand | BDBM50220741 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_87711 (CHEMBL697495) |
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| IC50 | 12187±n/a nM |
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| Citation |  Van Ommeslaeghe, K; Elaut, G; Brecx, V; Papeleu, P; Iterbeke, K; Geerlings, P; Tourwé, D; Rogiers, V Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition. Bioorg Med Chem Lett13:1861-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Histone deacetylase |
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| Name: | Histone deacetylase |
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| Synonyms: | Hdac5 | Hdac5 protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34754.92 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_104809 |
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| Residue: | 328 |
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| Sequence: | MHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKL
LQQKLSVGKVLIVDWDIHHGNGTQQAFYDDPSVLYISLHRYDNGNFFPGSGAPEEVGGGP
GVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLG
GYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAV
LQQKPSINAVATLEKVIEIQSKHWSCVQRFATGLGCSLREAQTGEKEEAETVSAMALLSM
GAEQAQAAATQEHSPRPAEEPMEQEPAL
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| BDBM50220741 |
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| n/a |
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| Name | BDBM50220741 |
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| Synonyms: | CHEMBL417594 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21N3O3 |
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| Mol. Mass. | 303.3562 |
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| SMILES | C[C@@H](NC(=O)c1ccc(cc1)N(C)C)\C=C\C=C\C(=O)NO |
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| Structure | 
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