| Reaction Details |
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 | Report a problem with these data |
| Target | cAMP-specific 3',5'-cyclic phosphodiesterase 4C |
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| Ligand | BDBM50221003 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157228 (CHEMBL769552) |
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| IC50 | 0.600000±n/a nM |
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| Citation |  Kim, E; Chun, HO; Jung, SH; Kim, JH; Lee, JM; Suh, BC; Xiang, MX; Rhee, CK Improvement of therapeutic index of phosphodiesterase type IV inhibitors as anti-Asthmatics. Bioorg Med Chem Lett13:2355-8 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C |
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| Name: | cAMP-specific 3',5'-cyclic phosphodiesterase 4C |
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| Synonyms: | Dpde1 | PDE4C_RAT | Pde4c |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60038.21 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_104732 |
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| Residue: | 536 |
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| Sequence: | NSSRTSSAASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGSATRQALLGTPPQSSQ
QAAPAEESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELTHLSETSR
SGNQVSEYISQTFLDQQAEVELPAPPTEDHPWPMAQITGLRKSCHTSLPTAAIPRFGVQT
DQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFRVLQERDLLKTFQIPADTLLRYL
LTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPG
VSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVID
MVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPL
PLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWAD
LVHPDAQELLDTLEDNREWYQSRVPCSPPHAIGPDRFKFELTLEETEEEEEEDERH
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|
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| BDBM50221003 |
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| n/a |
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| Name | BDBM50221003 |
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| Synonyms: | CHEMBL432348 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H19N3O3 |
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| Mol. Mass. | 277.319 |
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| SMILES | COc1ccc(\C=N\NC(N)=O)cc1OC1CCCC1 |
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| Structure | 
|
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