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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C
LigandBDBM50221806
Substrate/Competitorn/a
Meas. Tech.ChEMBL_155708
Ki 0.000070±n/a nM
Citation Temple DLYevich JPCatt JDOwens DHanning CCovington RRSeidehamel RJDungan KW Substituted 6,7-dihydroimidazo[1,2-a]purin-9(4H)-ones. J Med Chem 23:1188-98 (1980) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
Name:cAMP-specific 3',5'-cyclic phosphodiesterase 4C
Synonyms:DPDE1 | Dpde1 | Pde4c | cAMP-specific 3'',5''-cyclic phosphodiesterase 4C
Type:PROTEIN
Mol. Mass.:60038.21
Organism:Rattus norvegicus
Description:ChEMBL_104732
Residue:536
Sequence:
NSSRTSSAASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGSATRQALLGTPPQSSQ
QAAPAEESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELTHLSETSR
SGNQVSEYISQTFLDQQAEVELPAPPTEDHPWPMAQITGLRKSCHTSLPTAAIPRFGVQT
DQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFRVLQERDLLKTFQIPADTLLRYL
LTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPG
VSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVID
MVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPL
PLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWAD
LVHPDAQELLDTLEDNREWYQSRVPCSPPHAIGPDRFKFELTLEETEEEEEEDERH
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  Blast E-value cutoff:
BDBM50221806
n/a
NameBDBM50221806
Synonyms:CHEMBL18267
TypeSmall organic molecule
Emp. Form.C14H12ClN5O
Mol. Mass.301.731
SMILESClc1ccc(CN2C3=NCCN3C(=O)c3[nH]cnc23)cc1 |t:7|
Structure
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