| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M5 |
|---|
| Ligand | BDBM50228206 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_138640 (CHEMBL749271) |
|---|
| IC50 | 3.3±n/a nM |
|---|
| Citation |  Wilson, AA; Dannals, RF; Ravert, HT; Frost, JJ; Wagner, HN Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist. J Med Chem32:1057-62 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M5 |
|---|
| Name: | Muscarinic acetylcholine receptor M5 |
|---|
| Synonyms: | ACM5_MOUSE | Chrm5 | Muscarinic acetylcholine receptor | Muscarinic acetylcholine receptor M5 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60282.66 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_104873 |
|---|
| Residue: | 532 |
|---|
| Sequence: | MEGESYHNETTVNGTPVNHQALERHGLWEVITIAAVTAVVSLMTIVGNVLVMISFKVNSQ
LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWVLGSLACDLWLALDYVASNASVMN
LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLVSFILWAPAILCWQYLVGKRTVPP
DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVAEVK
KRKPAHRTLLRSFFSCPRPSLAQRVRNQASWSSSRRSTSTTGKPTQATDLSADWEKAEQV
TNCSSCPSSEDEAKATTDPVFQVVCKNEAKESPGKEFNTQETKETFVSPRTENNDYDTPK
YFLSPGAAHRLKSQKCVAYKFRLVVKADGTQETNNGCRKVKIMPCSFPVSKDPSTKGLDP
HLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLG
YWLCYVNSTINPICYALCNRTFRKTFKLLLLCRWKKKKVEEKLYWQGNSKLP
|
|
|
|---|
| BDBM50228206 |
|---|
| n/a |
|---|
| Name | BDBM50228206 |
|---|
| Synonyms: | Dexetimide | R-16470 [as hydrochloride] |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H26N2O2 |
|---|
| Mol. Mass. | 362.4647 |
|---|
| SMILES | O=C1CC[C@@](C2CCN(Cc3ccccc3)CC2)(C(=O)N1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
