| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM82247 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58977 (CHEMBL668642) |
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| Ki | 0.426580±n/a nM |
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| Citation |  Charifson, PS; Bowen, JP; Wyrick, SD; Hoffman, AJ; Cory, M; McPhail, AT; Mailman, RB Conformational analysis and molecular modeling of 1-phenyl-, 4-phenyl-, and 1-benzyl-1,2,3,4-tetrahydroisoquinolines as D1 dopamine receptor ligands. J Med Chem32:2050-8 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM82247 |
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| n/a |
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| Name | BDBM82247 |
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| Synonyms: | 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390) | CAS_87134-87-0 | CHEMBL2158641 | CHEMBL62 | SCH 23388 | SCH 23390 | SCH 23390 (R-enantiomer) | SCH 23390,R(+) |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18ClNO |
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| Mol. Mass. | 287.784 |
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| SMILES | CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| |
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| Structure | 
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