| Reaction Details |
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 | Report a problem with these data |
| Target | cAMP-dependent protein kinase catalytic subunit gamma |
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| Ligand | BDBM50228843 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_161403 (CHEMBL768312) |
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| IC50 | 3.0±n/a nM |
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| Citation |  Ricouart, A; Gesquiere, JC; Tartar, A; Sergheraert, C Design of potent protein kinase inhibitors using the bisubstrate approach. J Med Chem34:73-8 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| cAMP-dependent protein kinase catalytic subunit gamma |
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| Name: | cAMP-dependent protein kinase catalytic subunit gamma |
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| Synonyms: | KAPCG_HUMAN | PKA C-gamma | PRKACG | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic subunit gamma |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40442.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104720 |
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| Residue: | 351 |
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| Sequence: | MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
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| BDBM50228843 |
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| n/a |
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| Name | BDBM50228843 |
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| Synonyms: | CHEMBL436718 |
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| Type | Small organic molecule |
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| Emp. Form. | C53H94N28O12S |
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| Mol. Mass. | 1347.559 |
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| SMILES | NC(=N)NCCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)CCNCCNS(=O)(=O)c1cccc2cnccc12)C(O)=O |
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| Structure | 
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