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TargetcAMP-dependent protein kinase (PKA)
LigandBDBM50216682
Substrate/Competitorn/a
Meas. Tech.ChEMBL_161405
Ki 3000±n/a nM
Citation Ricouart AGesquiere JCTartar ASergheraert C Design of potent protein kinase inhibitors using the bisubstrate approach. J Med Chem 34:73-8 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
cAMP-dependent protein kinase (PKA)
Name:cAMP-dependent protein kinase (PKA)
Synonyms:PKA C-gamma | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma
Type:PROTEIN
Mol. Mass.:40442.03
Organism:Homo sapiens (Human)
Description:ChEMBL_104720
Residue:351
Sequence:
MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50216682
n/a
NameBDBM50216682
Synonyms:1-(5-Isoquinolinesulfonyl)-2-methylpiperazine | 1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine | 5-(2-methylpiperazine-1-sulfonyl)isoquinoline | CHEMBL323556 | cid_3542
TypeSmall organic molecule
Emp. Form.C14H17N3O2S
Mol. Mass.291.369
SMILESCC1CNCCN1S(=O)(=O)c1cccc2cnccc12
Structure
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