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TargetcAMP-dependent protein kinase (PKA)
LigandBDBM15203
Substrate/Competitorn/a
Meas. Tech.ChEMBL_161403
IC50 6000±n/a nM
Citation Ricouart AGesquiere JCTartar ASergheraert C Design of potent protein kinase inhibitors using the bisubstrate approach. J Med Chem 34:73-8 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
cAMP-dependent protein kinase (PKA)
Name:cAMP-dependent protein kinase (PKA)
Synonyms:PKA C-gamma | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma
Type:PROTEIN
Mol. Mass.:40442.03
Organism:Homo sapiens (Human)
Description:ChEMBL_104720
Residue:351
Sequence:
MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
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  Blast E-value cutoff:
BDBM15203
n/a
NameBDBM15203
Synonyms:5-(piperazine-1-sulfonyl)isoquinoline | CHEMBL75773 | Isoquinoline-5-sulfonic acid piperazin-1 ylamide | isoquinoline-5-sulfonamide 18
TypeSmall organic molecule
Emp. Form.C13H15N3O2S
Mol. Mass.277.342
SMILESO=S(=O)(N1CCNCC1)c1cccc2cnccc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: