| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
|---|
| Ligand | BDBM50230687 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_48424 (CHEMBL660352) |
|---|
| Ki | 3.9±n/a nM |
|---|
| Citation |  Higginbottom, M; Kneen, C; Ratcliffe, GS Rationally designed"dipeptoid" analogues of CCK. A Free-Wilson/Fujita-Ban analysis of some alpha-methyltryptophan derivatives as CCK-B antagonists. J Med Chem35:1572-7 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gastrin/cholecystokinin type B receptor |
|---|
| Name: | Gastrin/cholecystokinin type B receptor |
|---|
| Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49196.59 |
|---|
| Organism: | MOUSE |
|---|
| Description: | Cholecystokinin A CCKBR MOUSE::P56481 |
|---|
| Residue: | 453 |
|---|
| Sequence: | MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITL
YAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWL
LSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGL
ISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCY
VQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANT
WRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPR
ARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
|
|
|
|---|
| BDBM50230687 |
|---|
| n/a |
|---|
| Name | BDBM50230687 |
|---|
| Synonyms: | CHEMBL3351021 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H38N4O6 |
|---|
| Mol. Mass. | 574.6673 |
|---|
| SMILES | C[C@@H]1CCCC[C@H]1OC(=O)N[C@](C)(Cc1c[nH]c2ccccc12)C(=O)NC[C@H](NC(=O)\C=C\C(O)=O)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
