| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene B4 receptor 1/2 |
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| Ligand | BDBM50231628 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_74972 (CHEMBL684131) |
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| Ki | 77±n/a nM |
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| Citation |  Sofia, MJ; Floreancig, P; Bach, NJ; Baker, SR; Cockerham, SL; Fleisch, JH; Froelich, LL; Jackson, WT; Marder, P; Roman, CR o-phenylphenols: potent and orally active leukotriene B4 receptor antagonists. J Med Chem36:3978-81 (1993) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukotriene B4 receptor 1/2 |
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| Name: | Leukotriene B4 receptor 1/2 |
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| Synonyms: | Leukotriene B4 receptor |
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| Type: | n/a |
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| Mol. Mass.: | n/a |
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| Description: | ASSAY_ID of ChEMBL is 88360 |
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| Components: | This complex has 2 components. |
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| Component 1 |
| Name: | Leukotriene B4 receptor 2 |
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| Synonyms: | BLT2R | BLTR2 | LT4R2_HUMAN | LTB4 receptor JULF2 | LTB4-R 2 | LTB4-R2 | LTB4R2 | LTB4R2 protein | Leukotriene B4 | Leukotriene B4 R2 | Leukotriene B4 receptor | Leukotriene B4 receptor 2 | Leukotriene B4 receptor BLT2 | Leukotriene b1 | Seven transmembrane receptor BLTR2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37964.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Leukotriene 2 0 HUMAN::Q9NPC1 |
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| Residue: | 358 |
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| Sequence: | MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATL
VLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRC
LAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAA
HLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPY
HAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAG
PRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
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| Component 2 |
| Name: | Leukotriene B4 receptor 1 |
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| Synonyms: | BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37582.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15722 |
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| Residue: | 352 |
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| Sequence: | MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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| BDBM50231628 |
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| n/a |
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| Name | BDBM50231628 |
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| Synonyms: | CHEMBL130297 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28F3N4NaO2 |
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| Mol. Mass. | 484.4897 |
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| SMILES | [Na+].CCc1cc(c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1)-c1cccc(c1)C(F)(F)F |
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| Structure | 
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