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TargetCannabinoid receptor 1/Mu-type opioid receptor
LigandBDBM50009239
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1643866
IC50 50±n/a nM
Citation Chen SRKe YYYeh TKLin SYOu LCChen SCChang WTChang HFWu ZHHsieh CCLaw PYLoh HHShih CLai YKYeh SHUeng SH Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists. Eur J Med Chem 126:202-217 (2017) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 1/Mu-type opioid receptor
Name:Cannabinoid receptor 1/Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50009239
n/a
NameBDBM50009239
Synonyms:CHEMBL4092125
TypeSmall organic molecule
Emp. Form.C18H18Cl2N2O
Mol. Mass.349.254
SMILESCN1CCc2ccccc2C1CNC(=O)c1ccc(Cl)c(Cl)c1
Structure
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