Reaction Details | |||
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Target | Mu-type opioid receptor | ||
Ligand | BDBM50016452 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1643864 (CHEMBL3992793) | ||
EC50 | 1120±n/a nM | ||
Citation | Chen, SR; Ke, YY; Yeh, TK; Lin, SY; Ou, LC; Chen, SC; Chang, WT; Chang, HF; Wu, ZH; Hsieh, CC; Law, PY; Loh, HH; Shih, C; Lai, YK; Yeh, SH; Ueng, SH Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists. Eur J Med Chem126:202-217 (2017) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Mu-type opioid receptor | |||
Name: | Mu-type opioid receptor | ||
Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 44789.51 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P35372 | ||
Residue: | 400 | ||
Sequence: |
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BDBM50016452 | |||
n/a | |||
Name | BDBM50016452 | ||
Synonyms: | CHEMBL4100195 | ||
Type | Small organic molecule | ||
Emp. Form. | C19H28N2O | ||
Mol. Mass. | 300.4384 | ||
SMILES | CCC1CCC(CC1)C(=O)NCC1NCCc2ccccc12 |(20.45,-19.61,;20.44,-18.07,;21.77,-17.29,;21.76,-15.75,;23.09,-14.98,;24.43,-15.74,;24.44,-17.28,;23.11,-18.06,;25.75,-14.95,;27.1,-15.71,;25.74,-13.41,;24.4,-12.66,;24.39,-11.12,;25.72,-10.33,;25.7,-8.79,;24.37,-8.03,;23.04,-8.81,;21.7,-8.05,;20.37,-8.83,;20.38,-10.37,;21.72,-11.13,;23.05,-10.35,)| | ||
Structure |