| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50230205 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1644698 (CHEMBL3993627) |
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| Ki | >100±n/a nM |
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| Citation |  Bua, S; Di Cesare Mannelli, L; Vullo, D; Ghelardini, C; Bartolucci, G; Scozzafava, A; Supuran, CT; Carta, F Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis. J Med Chem60:1159-1170 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50230205 |
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| n/a |
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| Name | BDBM50230205 |
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| Synonyms: | CHEMBL4088636 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H23NO5 |
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| Mol. Mass. | 417.4538 |
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| SMILES | COc1ccc2cc(ccc2c1)[C@H](C)C(=O)NCCOc1ccc2oc(=O)ccc2c1 |r| |
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| Structure | 
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