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TargetCarbonic anhydrase 7
LigandBDBM50230205
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1644698
Ki>100±n/a nM
Citation Bua SDi Cesare Mannelli LVullo DGhelardini CBartolucci GScozzafava ASupuran CTCarta F Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis. J Med Chem 60:1159-1170 (2017) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 7
Name:Carbonic anhydrase
Synonyms:CA-VII | CA7 | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50230205
n/a
NameBDBM50230205
Synonyms:CHEMBL4088636
TypeSmall organic molecule
Emp. Form.C25H23NO5
Mol. Mass.417.4538
SMILESCOc1ccc2cc(ccc2c1)[C@H](C)C(=O)NCCOc1ccc2oc(=O)ccc2c1 |r|
Structure
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