| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50230369 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1644840 |
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| IC50 | 116±n/a nM |
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| Citation |  Iyer, MR; Cinar, R; Katz, A; Gao, M; Erdelyi, K; Jourdan, T; Coffey, NJ; Pacher, P; Kunos, G Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB J Med Chem60:1126-1141 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52842.52 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P47746 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50230369 |
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| n/a |
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| Name | BDBM50230369 |
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| Synonyms: | CHEMBL4079379 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H22Cl2FN5O2S |
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| Mol. Mass. | 594.487 |
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| SMILES | N\C(=N\C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1)c1ccc(F)cc1 |c:19| |
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| Structure | 
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